I see someone else posted a positive message so I wanted to do the same. I had 18 teeth pulled last Friday and full upper and lower immediate dentures placed. It's obvious every dentist has different guidelines during the healing process. Mine advised it is fine to use the adhesives during healing, but start sparingly and use in areas that won't be where the stitches are. I had to wear them for the first 24 hours without taking them out.
I had some pain the first day but when I woke up the next morning it was gone. I am trying to wear them as long as I can and have been successful in keeping them in pretty late in the evening. They told me the more you wear them the faster you will adjust.
Today I went for my post-op check up and told them I had a sore area in the front on top. The doctor looked at the denture and realized it was too high on my gumline so she adjusted it and I knew as soon as she put it in that was the issue.
The only "issue" I am having is learning to eat. She told me today that I am likely not using enough adhesive. My uppers are fine but my lowers come lose. They had given me all kinds of instruction before my procedure about how to eat, so I am working on that. It is best to eat on both sides of your mouth at the same time so the denture doesn't pop up on the opposite side. There is a learning curve there but I'm moving along and I expect in the next week or so I'll be doing just fine.
I have been living with pain and horrible, ugly teeth for 20 years and I am so happy that I now have a beautiful white smile. The care and eating will come along. I am very happy I finally made this decision!